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{{Synergy|Battery Powered}} If the player also has [[M16]], Shock Rifle and M16 are dual wielded.

becomes

Synergy Battery Powered - If the player also has M16, Shock Rifle and M16 are dual wielded.

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** After third use: '''MORE'''
 
** After third use: '''MORE'''
 
* The player cannot die by using Spice to drop below 1 heart container. However, using Spice after the player's health is at 1 heart container will prevent items that normally provide heart containers from adding heart containers until the sum of the player's starting heart containers and added heart containers minus the number of heart containers lost from Spice is greater than 1.
 
* The player cannot die by using Spice to drop below 1 heart container. However, using Spice after the player's health is at 1 heart container will prevent items that normally provide heart containers from adding heart containers until the sum of the player's starting heart containers and added heart containers minus the number of heart containers lost from Spice is greater than 1.
* If Spice is used by [[The Robot]], it will not add or remove armor, which makes Spice a very powerful item to be used when playing as The Robot.
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* If Spice is used by [[The Robot]], it will not add or remove armor, which makes spice a very powerful item to be used when playing as The Robot.
* Spice can replace the [[Prime Primer]] and the [[Gnawed Key]]. The player can buy it for 90 coins.
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*Spice can replace the [[Prime Primer]] and the [[Gnawed Key]]. The player can buy it for 90 coins.
* If the player has 40 Spice in their inventory, the game will stop spawning more Spice.
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*If the player has 40 Spice in their inventory, the game will stop spawning more Spice.
** If the player has the [[Knight's Gun]], Spice can still be dug up even after 40 have been obtained.
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**If the player has the [[Knight's Gun]], Spice can still be dug up even after 40 have been obtained.
* The effects of Spice do not persist in the Player's past.
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*The effects of Spice do not persist in the Player's past.
* Spice will spawn frequently even in Rainbow Mode including as boss rewards and in shops.
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*Spice will spawn frequently even in Rainbow Mode - including as boss rewards and in shops.
* Spice will only replace one item out of Rainbow Chests in a Rainbow Run.
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*Spice will only replace one item out of Rainbow Chests in a Rainbow Run.
* Spice can replace [[junk]]. <ref>[[:File:Spice-vs-junk.png|Spice replaces junk]]</ref>
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*Spice can replace junk. <ref>[[:File:Spice-vs-junk.png|Spice replaces junk]]</ref>
* Multiple Spice stacked in your inventory will only sell for the price of one Spice when sold to the Sell Creep.
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*Multiple Spice stacked in your inventory will only sell for the price of one Spice when sold to the Sell Creep
* There is a glitch where if the player saves the game after using Spice, then upon reloading at the next floor, the game will forget that Spice has been used.
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*There is a glitch where If the player saves the game after using Spice, then upon reloading at the next floor the game will forget that Spice has been used.
** The player will still retain the effects from previous uses of Spice: Heart containers, movement speed, etc.
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**The player will still retain the effects from previous uses of spice: Heart containers, movement speed, etc.
** Spice will stop replacing other items, and if it is found and used again, it will act as if it is the first time.
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**Spice will stop replacing other items, and if it is found and used again it will act as if it is the first time.
   
 
* If the person has [[Clone]], the Spice effects will persist even after dying.
 
* If the person has [[Clone]], the Spice effects will persist even after dying.
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