Laser Light Show - If the player also has Laser Rifle, Laser Rifle becomes blue and gold, and fires 3 sets of 3 shots in a spread per trigger pull. Each shot bounces once.
If all projectiles hit, damage is effectively increased by 65%.
This is significantly easier when used in conjunction with Remote Bullets or guns that home in on enemies.
A beam weapon used in conjunction with Scattershot will be split into three smaller beams, which will remain constant for as long as it is fired.
Explosion damage will not be affected by damage modifiers, including damage reduction. As such, Scattershot will massively buff explosive weapons.
Scattershot also allows you to fire 3 bullets with each shot during Winchester's game. Despite the reduced accuracy of each shot, this significantly improves the chances of hitting any targets.
Scattershot with Dark Marker's charge attack will cause the pellets to miss and not trigger the explosion. However, if the player has the synergy with Antibody, there is an extremely high chance the regular bullets will collide and trigger the blank effect.
With Helix Bullets, if Scattershot is picked up before Helix Bullets, four times the normal amount of projectiles are fired. However, if Helix Bullets is picked up first, six times the amount of projectiles are fired.
Regardless of the amount of bullets fired with Scattershot and Helix Bullets, each bullet does 36% of its original damage.