Enter the Gungeon Wiki
Type: Passive
Quality: B Quality Item.png
Sell Creep Price: 30 Money.png
Unlock Method: Purchase from Ox and Cadence for 10 Hegemony Credit.png.
Ammonomicon Entry
Gain armor when damaged several times.

These self-replicating Nanomachines transform lead that enters the body into armor.

Nanomachines is a passive item.


  • Grants two pieces of armor upon pickup.
  • Grants a piece of armor every 4 times damage is taken.


  • Synergy.png Future Gangster - If the player also has Thompson Sub-Machinegun, the projectiles are turned into lasers.
  • Synergy.png Pistol Machine - If the player also has Machine Pistol, its bullets will be connected by electricity.
  • Synergy.png Pretty Good - If the player also has SAA, the player's coolness will be increased by 2.
  • Synergy.png Production Model - If the player also has Prototype Railgun, its projectiles bounce up to 5 times.
  • Synergy.png Steel Skin - If the player also has AC-15, it will remain in its powered-up form even without armor.
  • If duplicates of this item are somehow obtained, allows the effect to happen on each separate Nanomachine.
    • Obtaining 4 Nanomachines allows the player to be invincible, as the amount of Nanomachines grants enough armor to negate the damage outright.


  • UnusedSynergy.png Unused: College Ball - If the player has Ballot, it causes an unknown effect.
  • The item name is a references to the nanomachines which Senator Armstrong uses in the final battle of the game "Metal Gear Rising: Revengence" and his famous quote: "Nanomachines, son!"
    • The item's function also references said quote, as they "harden in response to physical trauma", which in the game is represented by getting armor after getting hit.
    • The unused "College Ball" synergy also references Armstrong; the Ballot references the fact that Armstrong runs for president, and the name of the synergy is another one of his quotes: "Played college ball, ya know."
  • This item and function may also be a reference to Ratchet and Clank's Nanotech, which rebuilds the body whenever wounds are obtained in the series.
  • The synergy "Pretty Good" is a reference to the popular quote from Metal Gear Solid, "You're pretty good".
  • Its appearance may be a reference to the Nanites from Mystery Science Theater 3000.

See also[]