Challenge Mode



Challenge Mode is a mode introduced in the Supply Drop Update. In challenge mode, each room is affected by modifiers which make the game more challenging. Players can activate the Challenge Mode by speaking to Daisuke in The Breach and spending 6. Daisuke will be available to rescue after interacting with the Icosahedrax shrine 3 times or by freeing him from a cell after defeating the High Dragun once.

Each room can have 1 to 3 modifiers active at a time depending on the floor. Additionally, bosses in the Hollow and Forge have unique modifiers that increase their difficulty.

Reaching the Black Powder Mine in Challenge Mode will unlock Chance Bullets.

Defeating the High Dragun in Challenge Mode unlocks Chaos Bullets and unlocks Double Challenge Mode, which increases the number of modifiers in each room. It is activated by speaking to Daisuke again after enabling Challenge Mode.

After 30 attempts, the cost of Challenge Mode is reduced to 1 and Chaos Bullets are unlocked automatically if they haven't yet.

Unique Modifiers
Bosses in the Hollow and the Forge have special modifiers that modify their attack patterns.

Quotes
If Daisuke is spoken to after activating the mode, he will randomly say any number from 1 to 20. Some of them have special phrases:
 * 1: "Hahahaha... 1."
 * 13: "13. Bad luck, (character name)."
 * 14-16: Nothing special.
 * 17-19: The number with an exclamation mark.
 * 20: "20! Wow, that almost never happens!"

Trivia

 * Daisuke is a D20, a twenty-sided die that is commonly used in Dungeons and Dragons. When spoken to, his responses reference D&D wherein a 1 is a critical failure and a 20 is a critical success.
 * Blobulin Rancher is a reference to the game Slime Rancher.
 * Cursed Ceramics is a reference to Curse Jars from Dark Souls II.
 * Explosive Pyres is a reference to the game Destiny.
 * Ghost of the Shell is a reference to the anime Ghost In The Shell.
 * High Stress's effect and icon are a reference to the game Darkest Dungeon.
 * Long Live the King is a reference to the game Reigns and the movie The Lion King.
 * Extremely Bad Chess is a reference to the game Really Bad Chess.
 * Don't Blink is a reference to a Doctor Who episode.
 * Thermal Clips is a reference to the Mass Effect series.
 * Night's Watch is a reference to the Night's Watch who patrol the great Wall in George R.R. Martin's A Song of Ice and Fire, and its TV show adaptation Game of Thrones.
 * Dark was the Night is a reference to the song "Dark was the Night, Cold was the Ground" by Blind Willie Johnson.
 * Hammer Time is a reference to the catchphrase "Stop, Hammer Time" in the song "Can't Touch This" by MC HAMMER.
 * Something Wicked is part of a quote from Shakespeare's Macbeth.
 * Dragun Rage may be a reference to the Pokémon move Dragon Rage.
 * Daisuke's name is a pun on a common Japanese name and the English word 'dice'.